Following a theory that a particular gene could enable humans to become immune from the most common type of HIV, recruitment for gene therapy trials has began on February 3, 2009. This experimental treatment targets HIV patients who have had problems with drug resistance.
After the quest to find a cure for HIV has become close to futile, as the drugs that have been tested has actually increased risk of HIV infection, researchers have shifted their focus to developing a therapy that would enable humans to become resistant to HIV.
"We do have good treatment for HIV. That has been one of the most successful stories of the last 20 years in medicine," stated Pablo Tebas, an infectious disease expert at the University of Pennsylvania, in an interview with Wired.com. "However, over time, if the medications are not taken properly, individuals develop resistance to the HIV treatments, so they tend to have more limited therapeutic options."
This comes after the discovery of a small number of people who were exposed to HIV yet did not get infected. Scientists began working to discover the secret behind those people’s resistance (or possible immunity) against the virus, as well as how to make other people resistant to HIV.
They have discovered that most people have a gene called CCR5, making them vulnerable to HIV infections. Those who have natural resistance towards the virus, however, have a mutant CCR5 that inhibits HIV.
Scientists have also found that by cutting the CCR5 gene out of white blood cells, which are involved in our body’s immune response known as T-cells, they could protect a test-tube full of human cells. This gene editing technique relies on a type of proteins called zinc finger nucleases, which can delete any gene from a living cell. In theory, zinc finger nucleases could provide that amount of immunity to anyone.
The experimental treatment involves taking some healthy T-cells from an HIV patient, and then clipping out their CCR5 genes. Scientists then grow more of these edited T-cells in a dish before putting them back in the patient.
Tebas hopes that the results shown on the test-tube would also reflect in human experiments.
Posted in
I simply want to mention I am just very new to blogs and truly enjoyed you’re web page. Almost certainly I’m planning to bookmark your blog post . You definitely come with fabulous article content. Bless you for revealing your blog.
Check this out…
[...] that is the end of this article. Here you’ll find some sites that we think you’ll appreciate, just click the links over[...]……
cashier some form of voucher.grocery stores also…
have made it easy for the consumer to get coupons. they have dispensers in their aisles loaded with coupons applicable to the specific products on the shelf to which they are attached. a person forgetting their tomato sauce coupon at home…
Related……
[...]just beneath, are numerous totally not related sites to ours, however, they are surely worth going over[...]……
Websites worth visiting…
[...]here are some links to sites that we link to because we think they are worth visiting[...]……
It’s a shame you don’t have a donate button! I’d without a doubt donate to this outstanding blog! I guess for now i’ll settle for book-marking and adding your RSS feed to my Google account. I look forward to new updates and will share this blog with my Facebook group. Chat soon!
Bonjour…
You should take part in a contest for one of the best blogs on the web. I will recommend this site!…
Favorite link…
[...] Every now and then many of us choose blogs that we look over. Down the page are the best sites that we like [...]…
I am not sure where you are getting your info, but great topic. I needs to spend some time learning much more or understanding more. Thanks for magnificent info I was looking for this 301 Moved Permanently for my mission.
Fantastic weblog, I’m going to spend far more time reading about this topic
Cool webpage…
[...] The material talked about inside the article are some of the most beneficial to be found [...]…
the crea. there has been much debate…
as to how efficient the mls system currently is in the real estate market.many property sellers and buyers can now locate and sell homes right on the internet. this cuts out the need for the larger publicity that the mls system…
Websites you should visit…
[...]below you’ll find the link to some sites that we think you should visit[...]……
You should check this out…
[...] Wonderful story, reckoned we could combine a few unrelated data, nevertheless really worth taking a look, whoa did one learn about Mid East has got more problerms as well [...]……
of your services, as well as other…
details. this is in order to provide your clients with any up-to-date and accurate information that they require. your customers need not even know that they are speaking to an live answering service! virtual receptionists are able to give the impressi…
You should check this out…
[...] Wonderful story, reckoned we could combine a few unrelated data, nevertheless really worth taking a look, whoa did one learn about Mid East has got more problerms as well [...]……
Thank you, I have recently been looking for information about this topic for a long time and yours is the greatest I have discovered so far. However, what concerning the bottom line? Are you positive in regards to the supply?
Awesome website…
[...]the time to read or visit the content or sites we have linked to below the[...]……
hey great post. I love good and truthful content. Thanks for the information!
This is a fantastic source of ideas that you are sharing with. I enjoy seeing web pages like this with full of satisfactory words and phrases that will help me into my project. Thanks!
Recent Blogroll Additions……
[...]usually posts some very interesting stuff like this. If you’re new to this site[...]……
Sites we Like……
[...] Every once in a while we choose blogs that we read. Listed below are the latest sites that we choose [...]……
Superb website…
[...]always a big fan of linking to bloggers that I love but don’t get a lot of link love from[...]……
Wonderful goods from you, man. 301 Moved Permanently I have understand your stuff previous to and you’re just too fantastic. I really like what you have acquired here, really like what you’re saying and the way in which you say it. You make it enjoyable and you still take care of to keep it wise. I can not wait to read far more from you. This is really a tremendous 301 Moved Permanently informations.
Check this out…
[...] that is the end of this article. Here you’ll find some sites that we think you’ll appreciate, just click the links over[...]……
Looking around……
[...] So many males and females have got total-time attribute and are going to be undertaking an occupation exchange [...]…
Online Article……
[...]The information mentioned in the article are some of the best available [...]……
Superb webpage…
[...] Listed are some of the sites we strongly recommend for our guests [...]…
Recent Blogroll Additions……
[...]usually posts some very interesting stuff like this. If you’re new to this site[...]……
Worthy sites…
[...] pursuing are a few links to online sites which I connect to because we do recognize these are worthwhile looking into [...]…
Fantastic goods from you, man. 301 Moved Permanently I’ve understand your stuff previous to and you’re just too excellent. I really like what you have acquired here, really like what you’re stating and the way in which you say it. You make it entertaining and you still care for to keep it wise. I can’t wait to read much more from you. This is actually a tremendous 301 Moved Permanently informations.
dehydrated and have enough water. water plays…
an essential role in enhancing the body’s metabolic system and eventually burning up fats. but do not get it twisted, when experts talk about eight to ten glasses of water in a day, it has nothing to do with yogurt, they…
Great website…
[...]we like to honor many other internet sites on the web, even if they aren’t linked to us, by linking to them. Under are some webpages worth checking out[...]……
301 Moved Permanently I was recommended this blog by my cousin. I’m not sure whether this post is written by him as nobody else know such detailed about my trouble. You’re amazing! Thanks! your article about 301 Moved PermanentlyBest Regards Agata
abo…
I couldn’t resist commenting…
Great website…
[...]we like to honor many other internet sites on the web, even if they aren’t linked to us, by linking to them. Under are some webpages worth checking out[...]……
301 Moved Permanently I was suggested this website by my cousin. I’m not sure whether this post is written by him as no one else know such detailed about my trouble. You’re wonderful! Thanks! your article about 301 Moved PermanentlyBest Regards Cassetta
This is the punish 301 Moved Permanently journal for anyone who wants to act out out almost this topic. You attending so untold its nigh wearying to reason with you (not that I truly would want…HaHa). You definitely put a new whirl on a message thats been cursive virtually for geezerhood. Good nonsensicality, only enthusiastic!
Websites worth visiting…
[...]here are some links to sites that we link to because we think they are worth visiting[...]……
Awesome website…
[...]the time to read or visit the content or sites we have linked to below the[...]……
Gems form the internet…
[...]very few websites that happen to be detailed below, from our point of view are undoubtedly well worth checking out[...]……
I just saved Trial for HIV Gene Therapy Begins | VD on Digg, hope this helps get you more visitors. Correct because of this write-up, I truly think this site requires a lot more due consideration. I’ll probably be returning again to read more, thanks for the article it is superb
Hi…
It’s hard to find knowledgeable people on this topic, but you sound like you know what youfre talking about! Thanks…
truyen ma, nghe doc truyen ma kinh di…
I must tell this is good place. truyen ma kinh di…
Howdy this is kinda of off topic but I was wondering if blogs use WYSIWYG editors or if you have to manually code with HTML. I’m starting a blog soon but have no coding skills so I wanted to get guidance from someone with experience. Any help would be enormously appreciated!
Very interesting details you have mentioned , thanks for posting . “Lefty Wise guy dont carry wallets, they carry their money in a roll….beaner on the outs” by Donnie Brasco.
Check this out…
[...] that is the end of this article. Here you’ll find some sites that we think you’ll appreciate, just click the links over[...]……
Gems form the internet…
[...]very few websites that happen to be detailed below, from our point of view are undoubtedly well worth checking out[...]……
game avatar. huong dan choi game avatar tren may tinh…
I want to thanks this page good website. game avatar 2.0…
Great blog…
The next time I read a blog, I hope that it doesnt disappoint me as much as this one. I mean, I know it was my choice to read, but I actually thought youd have something interesting to say. All I hear is a bunch of whining about something that you coul…